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Historical Snapshot Video

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What is Smallpox?

Smallpox is a life-threatening infectious disease primarily affecting humans. Most people contract the virus via human-to-human contact. Other possible transmissions may include contact with scabs, or tissue from an infected person. 

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The first symptom of smallpox is a fever, followed by the skin lesions that eventually affect most of the body. As seen in this image of a mother and child, small pox has a devastating affect on the skin, which is the largest organ in the human body. Survivors can be pock-scarred from the severity of the skin lesions.​

In some cases bone lesions occur in tandem with smallpox. These lesions are known in medical terms as osteomyelitis variolosa. Osteomyelitis variolosa is a complication of smallpox variola virus and is most commonly found occurring in children up until the time of puberty when the bones mature and harden. 

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The lesions will begin on the inside of the bone near the metaphysis or the growth plate, and can push the bone outwards obliterating the structure as the graphic shows. 

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Bone Lesions
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